Syndrome of pain and stiffness, usually in neck, shoulders and hips. Associated with the HLA-DR4 and Giant Cell Arteritis .

The cause is unknown but there is suggestion of environmental factor possibly a virus causes immune activation in genetically predisposed patients

Symmetrical joint stiffness, low grade fever and weight loss.

Joint stiffness, malaise, fatigue, Difficulty completing daily life activities, Morning stiffness for more than 1 hour, Muscle stiffness after prolonged inactivity

Bloods: FBC, ANA, RF, and CK – Usually normal

Raised ESR is the most sensitive test for PMR

Medical: Low dose Corticosteroids 

With prompt diagnosis and adequate therapy, patients have an excellent prognosis. The average length of disease is 3 years

Associated with development of Giant cell Arteritis