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Pathology

Tear in the tunica intima allowing blood between the inner and outer layers producing luminal stenosis, complete occlusion or clot embolism compromising blood supply to the brain
Accounts for nearly a quarter of strokes in young patients

Aetiology

Spontaneous: Associated with Ehlers Danlos, Marfan’s, fibromuscular dysplasia
Traumatic: Head injury, RTA, chiropractic manipulation

Signs

Horner’s syndrome, scalp tenderness, pulsatile tinnitus, cranial neuropathies and subarachnoid hemorrhage 

Symptoms

Ipsilateral headache, neck pain.

Investigations

Imaging: CT or MRA.
Formal cerebral angiography is the gold standard investigation standard investigation  

Treatment

Medical: Aspirin or warfarin 
Surgical: Angioplasty and stenting may be considered with dissection presenting 
with recurrent thromboembolism

Prognosis

Extracranial dissections have a better prognosis than intracranial types. 50% of cases have no neurological deficit. 4% mortality.
Ischaemic stroke

Key Facts

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Key Images

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Key References

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