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Pathology
A group of viral infections which have broadly similar clinical features, are highly infectious in nosocomial settings and carry significant mortality. Consider VHF in all travellers developing fever within 3 weeks of travel to endemic area.
Aetiology
Lassa fever, Crimean-Congo haemorrhagic fever, Ebola, Marburg. Infection from animal vectors, in Ebola this is a bat.
Signs
Petechiae, oedema, hypotension, flushing, conjunctival injection.
Symptoms
Fever, malaise, vomiting, mucosal and gastrointestinal (GI) bleeding.
Investigations
Bloods: Blood film to exclude malaria, FBC, U&E, Clotting
Treatment
Conservative: Isolation of patient
Administration: Requires transfer of patient to tertiary infectious diseases unit
and notification to appropriate authorities.
Prognosis
Very high mortality.
Shock, circulatory collapse, death.
Retinitis, orchitis, deafness, hepatitis, transverse myelitis, renal failure and uveitis
Key Facts
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Key Images
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Key References
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