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Pathology
Chronic relapsing functional bowel disorder, constipation predominant, diarrhoea predominant or alternate between the two.
Aetiology
Unknown, IBS is common, highest prevalence in young women
Altered motility and visceral hypersensitivity are implicated in causing the symptoms of IBS
Signs
Abdominal bloating, Sensation of incomplete defecation
Symptoms
Diarrhoea, constipation, abdominal pain, bloating, relieved by defecation, passing mucous, increased flatulence
Investigations
Bloods: FBC, U&E, TFTs, Faecal Calprotectin – marker of bowel inflammation
Auto-Antibody Screen: Tissue Transglutamase and Anti-endomysial negative
Microbiology: Stool culture.Treatment
Conservative: Lifestyle advice
Medical: Antispasmodics for pain, anti-diarrhoeal agents, laxatives
Prognosis
50% improve after 1 year.
Can lead to anxiety and depression
Key Facts
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Key References
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