Chronic relapsing functional bowel disorder, constipation predominant, diarrhoea predominant or alternate between the two.
Unknown, IBS is common, highest prevalence in young women
Altered motility and visceral hypersensitivity are implicated in causing the symptoms of IBS
Abdominal bloating, Sensation of incomplete defecation
Diarrhoea, constipation, abdominal pain, bloating, relieved by defecation, passing mucous, increased flatulence
Bloods: FBC, U&E, TFTs, Faecal Calprotectin – marker of bowel inflammation
Auto-Antibody Screen: Tissue Transglutamase and Anti-endomysial negativeMicrobiology: Stool culture.
Conservative: Lifestyle advice
Medical: Antispasmodics for pain, anti-diarrhoeal agents, laxatives
50% improve after 1 year.
Can lead to anxiety and depression