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Pathology
Single stranded RNA virus
Aetiology
Faeco-orally (contaminated food, water). Incubation time 2-6 weeks
Signs
Jaundice, lymphadenopathy, hepatomegaly, splenomegaly
Symptoms
Malaise, anorexia, nausea, vomiting, diarrhoea, headache, abdominal pain
Investigations
Bloods: LFTs show a raised AST, ALT and bilirubin
Serology: Hepatitis A IgM Positive
Imaging: Ultrasound Liver to exclude other causes of acute liver injury
Treatment
Conservative: Usually self-limiting
Vaccination: Immunisation for high risk patients leads to lifelong immunity
Prognosis
Good prognosis with a 0.1% mortality.
Myocarditis, arthritis, vasculitis
Key Facts
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Key References
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