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Pathology

Single stranded RNA virus

Aetiology

Faeco-orally (contaminated food, water). Incubation time 2-6 weeks

Signs

Jaundice, lymphadenopathy, hepatomegaly, splenomegaly

Symptoms

Malaise, anorexia, nausea, vomiting, diarrhoea, headache, abdominal pain

Investigations

Bloods: LFTs show a raised AST, ALT and bilirubin
Serology: Hepatitis A IgM Positive
Imaging: Ultrasound Liver to exclude other causes of acute liver injury

Treatment

Conservative: Usually self-limiting
Vaccination: Immunisation for high risk patients leads to lifelong immunity

Prognosis

Good prognosis with a 0.1% mortality.
Myocarditis, arthritis, vasculitis

Key Facts

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Key References

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