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Pathology
Episodes of apnoea during sleep caused by collapse/obstruction of the pharyngeal airways, terminated by partial waking resulting in fragmented sleep
Aetiology
Most commonly seen in overweight, middle-aged men and is made worse by alcohol. Upper airways abnormalities e.g. large tonsils, can sometimes be the causes.
Signs
Overweight
Symptoms
Daytime sleepiness, morning headaches, disturbed sleep, decreased libido, partners will report snoring and apnoea
Investigations
Epworth Sleep Scale is a questionnaire designed to measure daytime sleepiness. Overnight pulse oximetry will show frequent desaturations which resolve on waking. Sleep studies may be needed if overnight oximetry not diagnostic.
Treatment
Reduce weight and avoid alcohol, continuous positive airways pressure (CPAP)
Surgery is sometimes used to correct upper airways abnormalities.Prognosis
Dependent on development of vascular complications, can resolve if sufficient weight loss
Pulmonary hypertension leading to cor pulmonale, hypertension, type 2 respiratory failure
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Key References
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