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Pathology
Systemic autoimmune disease that causes destruction of exocrine glands
Aetiology
Primary or secondary in other autoimmune rheumatic
Signs
Xeroderma (dry skin), angular stomatitis, eye redness
Schirmer’s Test - Poor tear production.Symptoms
Dry eyes, dry/sore mouth, mild polyarthritis, malaise
Investigations
Bloods: Raised ESR, Rheumatoid Factor Positive, Positive anti-Ro/La
Treatment
Conservative: Artificial tears and saliva
Prognosis
Generally good
Pancreatitis, interstitial nephritis, renal tubular acidosis, glomerulonephritis, B-cell lymphomas
Key Facts
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Key Images
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Key References
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