Reading Time:

Pathology

Fat soluble vitamin, found in liver, kidney, eggs and green vegetables. Role in corneal and conjunctival development 

Aetiology

Rare in the industrialised world but more common in developing countries 
Can occur in diseases causing malabsorption including chronic pancreatitis, coeliac disease, Crohn’s disease and cystic fibrosis due to fat malabsorption

Signs

Xerophthalmia (due to impaired lacrimal gland function and results in dry eyes, night blindness and can even result in total blindness)

Symptoms

Poor vision at night, dry eyes 

Investigations

Clinical diagnosis

Treatment

Medical: Vitamin A supplements, pancreatic enzyme supplements if secondary to 
fat malabsorption due to pancreatic insufficiency 

Prognosis

Usually reversible, advanced xerophthalmia can be irreversible
Night blindness.

Key Facts

Lorem ipsum dolor sit amet, sapien platea morbi dolor lacus nunc, nunc ullamcorper. Felis aliquet egestas vitae, nibh ante quis quis dolor sed mauris.

Key Images

Lorem ipsum dolor sit amet, sapien platea morbi dolor lacus nunc, nunc ullamcorper. Felis aliquet egestas vitae, nibh ante quis quis dolor sed mauris.

Key References

Lorem ipsum dolor sit amet, sapien platea morbi dolor lacus nunc, nunc ullamcorper. Felis aliquet egestas vitae, nibh ante quis quis dolor sed mauris.