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Pathology
Fat soluble vitamin, found in liver, kidney, eggs and green vegetables. Role in corneal and conjunctival development
Aetiology
Rare in the industrialised world but more common in developing countries
Can occur in diseases causing malabsorption including chronic pancreatitis, coeliac disease, Crohn’s disease and cystic fibrosis due to fat malabsorption
Signs
Xerophthalmia (due to impaired lacrimal gland function and results in dry eyes, night blindness and can even result in total blindness)
Symptoms
Poor vision at night, dry eyes
Investigations
Clinical diagnosis
Treatment
Medical: Vitamin A supplements, pancreatic enzyme supplements if secondary to
fat malabsorption due to pancreatic insufficiency
Prognosis
Usually reversible, advanced xerophthalmia can be irreversible
Night blindness.Key Facts
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Key Images
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Key References
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