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Pathology
RNA virus
Aetiology
Exchange of body fluids: sexual intercourse, vertical transmission from mother to baby, needle sharing, needle stick, blood transfusion. Incubation time 2-3 months
Signs
Jaundice
Symptoms
Usually asymptomatic, lethargy, malaise and anorexia
Investigations
Bloods: LFTs show raised AST and ALT
Microbiology: Hepatitis C PCR, viral load and genotyping
Treatment
Medical: Pegylated Interferon-alpha, Ribavirin
Surgical: Liver transplantation
Prognosis
Risk of hepatocellular carcinoma and cirrhosis
80% progress to chronic infection
Key Facts
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Key Images
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Key References
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