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Pathology
Brief episodes of focal brain, spinal cord or retinal ischemia with clinical symptoms usually lasting less than a 24 hours and without evidence of acute infarction.
Aetiology
Non-modifiable risk factors: Age > 65, male gender, family history
Modifiable risk factors: Hypertension, diabetes, smoking, hypercholesterolemia,
atrial fibrillation, obesityis.Signs
Often have resolved by examination, but hemiparesis, visual loss, sensory symptoms and speech impairment may still be present
Symptoms
These depend on the areas of brain involved and can present as brief episodes of visual loss, speech disturbance, hemiparesis or sensory symptoms
Investigations
Bloods: FBC, U&E, Calcium, Magnesium, lipid profile, glucose, TFTs
Imaging: CT or MRI brain – assess for ischaemic changes
Carotid Doppler – assess for carotid stenosis
ECG: Assess for arrhythmias; may require 24 hour tape
Echo: Assess for structural abnormality and valve function
Treatment
Address modifiable risk factors, antiplatelets (aspirin, clopidogrel), statin and antihypertensives.
Prognosis
ABCD2 score
15% strokes preceded by TIA
Key Facts
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Key References
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