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Pathology

Joints can be invaded by pathogens (most commonly bacteria) via different routes. Most commonly via bloodstream or direct inoculation in trauma.

Aetiology

Previously damaged or prosthetic joints and those associated with the presence of inflammatory arthritis conditions are more susceptible

Signs

Fever, joint pain, oedema, erythema, warmth and decreased movement

Symptoms

Joint pain, erythema, swelling and warmth

Investigations

Bloods: FBC, U&E, CRP, Blood Cultures and Uric Acid
Imaging: X-Ray to exclude osteomyelitis or signs of crystal arthropathy
Joint Aspiration: Cloudy synovial fluid with Raised White Cell Count

Treatment

Medical: IV antibiotics (after joint aspiration), analgesia, 
Surgical: Referral to orthopaedics if prosthetic joint

Prognosis

Predictors of poor outcome in suppurative arthritis include the following:
Age older than 60 years
Infection of the hip or shoulder joints
Underlying rheumatoid arthritis
Positive findings on fluid cultures after 7 days of appropriate therapy
Delay of 7 days or longer in instituting therapy
50% have significant sequelae of decreased range of motion or chronic pain after infection.  Also dysfunctional joints, osteomyelitis, and sepsis 

Key Facts

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Key References

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